In any case, COVID certificates are used less commonly now. However, this may be difficult to implement as infection surveillance has decreased in most countries compared with earlier in the pandemic. The authors suggest a person's previous infection status and timing should be considered alongside their booster vaccinations to predict protection.
This means it would take many more mutations in the virus genome to completely evade T cell immunity. A type of immune cells called T cells recognise snippets of virus proteins rather than intact proteins. Thankfully, we don't just rely on antibodies for protection. Evasion from neutralizing antibodies explains our failure to control reinfection by omicron variants. Omicron lineages have enough mutations to differentiate substantially from previous variants, and therefore evade existing antibodies. These Y-shaped molecules recognise intact proteins of the virus exterior and attach to them, preventing the virus from latching on to the cell receptor necessary for infection.īut to persist, viruses like SARS-CoV-2 introduce random mutations in their genome when they replicate, aiming to continuously alter their proteins to escape immune recognition. By way of background, neutralizing antibodies generated after previous viral infection are important to prevent subsequent virus entry to susceptible cells.
0 kommentar(er)
